IL-33 Expression Is Lower in Current Smokers at Both Transcriptomic and Protein Level
- Creator: Faiz, Alen , Mahbub, Rashad M. , Heijink, Irene H. , Massip, Florian , de Biase, Maria Stella , Schwarz, Roland F. , Adcock, Ian M. , Chung, Kian F. , van der Does, Anne , Hiemstra, Pieter S. , Goulaouic, Helene , Xing, Heming , Boedijono, Fia Sabrina , Wark, Peter A. , ., , Tomassen, Milan I. , Kooistra, Wierd , Timens, Wim , Nawijn, Martijn , Hansbro, Philip M. , Johansen, Matt D. , Pouwels, Simon D.
- Resource Type: journal article
- Date: 2023
Adverse roles of mast cell chymase-1 in chronic obstructive pulmonary disease
- Creator: Liu, Gang , Jarnicki, Andrew G. , Paudel, Keshav R. , Lu, Wenying , Wadhwa, Ridhima , Philp, Ashleigh M. , Van Eeckhoutte, Hannelore , Marshall, Jacqueline E. , Malyla, Vamshikrishna , Katsifis, Angelica , Fricker, Michael , Hansbro, Nicole G. , Dua, Kamal , Kermani, Nazanin Z. , Eapen, Mathew S. , Tiotiu, Angelica , Chung, K. Fan , Caramori, Gaetano , Bracke, Ken , Adcock, Ian M. , Wark, Peter A. , Hansbro, Philip M.
- Resource Type: journal article
- Date: 2022
Adverse roles of mast cell chymase-1 in COPD
- Creator: Liu, Gang , Jarnicki, Andrew G. , Fricker, Michael , Hansbro, Nicole G. , Dua, Kamal , Kermani, Nazanin Z. , Eapen, Mathew S. , Tiotiu, Angelica , Chung, K. Fan , Caramori, Gaetano , Bracke, Ken , Adcock, Ian M. , Paudel, Keshav R. , Sohal, Sukhwinder S. , Wark, Peter A. , Oliver, Brian G. , Hansbro, Philip M. , Lu, Wenying , Wadhwa, Ridhima , Philp, Ashleigh M. , Van Eeckhoutte, Hannelore , Marshall, Jacqueline E. , Malyla, Vamshikrishna , Katsifis, Angelica
- Resource Type: journal article
- Date: 2022
Pathways linked to unresolved inflammation and airway remodelling characterize the transcriptome in two independent severe asthma cohorts
- Creator: Sánchez-Ovando, Stephany , Pavlidis, Stelios , Wark, Peter A. B. , Kermani, Nazanin Zounemat , Baines, Katherine Joanne , Barker, Daniel , Gibson, Peter G. , Wood, Lisa G. , Adcock, Ian M. , Chung, Kian Fan , Simpson, Jodie Louise
- Resource Type: journal article
- Date: 2022
Relationship between type 2 cytokine and inflammasome responses in obesity-associated asthma
- Creator: Pinkerton, James W. , Kim, Richard Y. , Baines, Katherine J. , Starkey, Malcolm R. , Kermani, Nazanin Z. , Guo, Yi-Ke , Robertson, Avril A. B. , O'Neill, Luke A. J. , Adcock, Ian M. , Cooper, Matthew A. , Gibson, Peter G. , Wood, Lisa G. , Brown, Alexandra C. , Hansbro, Philip M. , Horvat, Jay C. , Rae, Brittany E. , Donovan, Chantal , Mayall, Jemma R. , Carroll, Olivia R. , Ali, Md. Khadem , Scott, Hayley A. , Berthon, Bronwyn S.
- Resource Type: journal article
- Date: 2022
Sputum macrophage diversity and activation in asthma: Role of severity and inflammatory phenotype
- Creator: Tiotiu, Angelica , Zounemat Kermani, Nazanin , Badi, Yusef , Pavlidis, Stelios , Hansbro, Philip M. , Guo, Yi-Ke , Chung, Kian Fan , Adcock, Ian M.
- Resource Type: journal article
- Date: 2021
Host-microbe cross-talk in the lung microenvironment: implications for understanding and treating chronic lung disease
- Creator: Gosens, Reinoud , Hiemstra, Pieter S. , Adcock, Ian M. , Bracke, Ken R. , Dickson, Robert P. , Hansbro, Philip M. , Krauss-Etschmann, Ssusanne , Smits, Hermelijn H. , Stassen, Frank R. M. , Bartel, Sabine
- Resource Type: journal article
- Date: 2020
Management of severe asthma: a European Respiratory Society/American Thoracic Society guideline
- Creator: Holguin, Fernando , Cardet, Juan Carlos , Chung, Kian Fan , Diver, Sarah , Ferreira, Diogenes S. , Fitzpatrick, Anne , Gaga, Mina , Kellermeyer, Liz , Khurana, Sandhya , Knight, Shandra , McDonald, Vanessa M. , Morgan, Rebecca L. , Ortega, Victor E. , Rigau, David , Subbarao, Padmaja , Tonia, Thomy , Adcock, Ian M. , Bleecker, Eugene R. , Brightling, Chris , Boulet, Louis-Philippe , Cabana, Michael , Gibson, Peter
- Resource Type: journal article
- Date: 2020
New drugs under development for COPD
- Creator: Lo Bello, Federica , Hansbro, Philip M. , Donovan, Chantal , Coppolino, Irene , Mumby, Sharon , Adcock, Ian M. , Caramori, Gaetano
- Resource Type: journal article
- Date: 2020
Cellular mechanisms underlying steroid-resistant asthma
- Creator: Wadhwa, Ridhima , Dua, Kamal , Adcock, Ian M. , Horvat, Jay C. , Kim, Richard Y. , Hansbro, Philip M.
- Resource Type: journal article
- Date: 2019
CSF3R/CD114 mediates infection-dependent transition to severe asthma
- Creator: Wang, Hao , FitzPatrick, Meaghan , Adcock, Ian M. , Chung, Kian Fan , Anderson, Gary P. , Vlahos, Ross , Wark, Peter , Bozinovski, Steven , Wilson, Nicholas J. , Anthony, Desiree , Reading, Patrick C. , Satzke, Catherine , Dunne, Eileen M. , Licciardi, Paul V. , Seow, Huei Jiunn , Nichol, Kristy
- Resource Type: journal article
- Date: 2019
Functional effects of the microbiota in chronic respiratory disease
- Creator: Budden, Kurtis F. , Shukla, Shakti D. , Hansbro, Philip M. , Rehman, Saima Firdous , Bowerman, Kate L. , Keely, Simon , Hugenholtz, Philip , Armstrong-James, Darius P. H. , Adcock, Ian M. , Chotirmall, Sanjay H. , Chung, Kian Fan
- Resource Type: journal article
- Date: 2019
IL-22 and its receptors are increased in human and experimental COPD and contribute to pathogenesis
- Creator: Starkey, Malcolm R. , Plank, Maximilian W. , Donovan, Chantal , Hansbro, Nicole G. , Nguyen, Duc H. , Nair, Prema Mono , Kim, Richard Y. , Horvat, Jay C. , Kaiko, Gerard E. , Durum, Scott K. , Wark, Peter A. , Sin, Don D. , Casolari, Paolo , Caramori, Gaetano , Adcock, Ian M. , Foster, Paul S. , Hansbro, Philip M. , Papi, Alberto , Pavlidis, Stelios , Guo, Yike , Cameron, Guy J. M. , Haw, Tatt Jhong , Tam, Anthony , Obiedat, Maen
- Resource Type: journal article
- Date: 2019
Mitochondrial ROS and NLRP3 inflammasome in acute ozone-induced murine model of airway inflammation and bronchial hyperresponsiveness
- Creator: Xu, Mengmeng , Wang, Lei , Chung, Kian Fan , Li, Feng , Wang, Muyun , Wang, Hanying , Zhang, Hai , Chen, Yuqing , Wang, Xiaohui , Gong, Jicheng , Zhang, Junfeng , Adcock, Ian M.
- Resource Type: journal article
- Date: 2019
Molecular links between COPD and lung cancer: new targets for drug discovery?
- Creator: Caramori, Gaetano , Ruggeri, Paolo , Tuccari, Giovanni , Hansbro, Philip M. , Adcock, Ian M. , Mumby, Sharon , Ieni, Antonio , Lo Bello, Federica , Chaminka, Vrushali , Donovan, Chantal , Andò, Filippo , Nucera, Francesco , Coppolino, Irene
- Resource Type: journal article
- Date: 2019
Toll-like receptor 2 and 4 have opposing roles in the pathogenesis of cigarette smoke-induced chronic obstructive pulmonary disease
- Creator: Haw, Tatt Jhong , Starkey, Malcolm R. , Horvat, Jay C. , Adcock, Ian M. , Hansbro, Philip M. , Pavlidis, Stelios , Fricker, Michael , Arthurs, Anya L. , Nair, Prema M. , Liu, Gang , Hanish, Irwan , Kim, Richard Y. , Foster, Paul S.
- Resource Type: journal article
- Date: 2018
Animal models of COPD: what do they tell us?
- Creator: Jones, Bernadette , Donovan, Chantal , Hansbro, Philip M. , Liu, Gang , Gomez, Henry M. , Chimankar, Vrushali , Harrison, Celese L. , Wiegman, Cornelis H. , Adcock, Ian M. , Knight, Darryl A. , Hirota, Jeremy A.
- Resource Type: journal article
- Date: 2017
Is mitochondrial dysfunction a driving mechanism linking COPD to nonsmall cell lung carcinoma?
- Creator: Ng Kee Kwong, Francois , Nicholson, Andrew G. , Harrison, Celeste L. , Hansbro, Philip M. , Adcock, Ian M. , Chung, Kian Fan
- Resource Type: journal article
- Date: 2017
MicroRNA-21 drives severe, steroid-insensitive experimental asthma by amplifying phosphoinositide 3-kinase-mediated suppression of histone deacetylase 2
- Creator: Kim, Richard Y. , Horvat, Jay C. , Sunkara, Krishna P. , Nguyen, Thi Hiep , Jarnicki, Andrew G. , Keely, Simon , Mattes, Joerg , Adcock, Ian M. , Foster, Paul S. , Hansbro, Philip M. , Pinkerton, James W. , Starkey, Malcolm R. , Essilfie, Ama T. , Mayall, Jemma R. , Nair, Prema M. , Hansbro, Nicole G. , Jones, Bernadette , Haw, Tatt Jhong
- Resource Type: journal article
- Date: 2017
The MIF antagonist ISO-1 attenuates corticosteroid-insensitive inflammation and airways hyperresponsiveness in an ozone-induced model of COPD
- Creator: Russell, Kirsty E. , Chung, Kian Fan , Starkey, Malcolm R. , Hansbro, Philip M. , Adcock, Ian M. , Wiegman, Coen H. , Clarke, Colin J. , Durham, Andrew L. , Mallia, Patrick , Footit, Joseph , Johnston, Sebastian L. , Barnes, Peter J. , Hall, Simon R. , Simpson, Karen D.
- Resource Type: journal article
- Date: 2016